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Article

NMR methods for detection of small molecule binding to RGS4.

Methods in enzymology - 1 Jan 2013

Storaska Andrew J, Neubig Richard R

Abstract excerpt

The duration and amplitude of G-protein-coupled receptor (GPCR) signaling is controlled by regulator of G-protein signaling (RGS) proteins. The 20 RGS family members act as GTPase accelerating proteins through their interaction with the Gα subunit of the Gαβγ heterotrimer. Their influence over GPCR signaling has attracted many to these proteins as advantageous therapeutic targets. The nature of the RGS structure...

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Source

Identifiers

PMID: 23374184
DOI: 10.1016/B978-0-12-407865-9.00008-X

Genes

RGS4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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