Isolation and characterization of a novel human RGS mutant displaying gain-of-function activity.

Abstract excerpt

Regulator of G protein signaling (RGS) proteins play a crucial role in the adaptation of cells to stimulation by G protein-coupled receptors via heterotrimeric G proteins. Alterations in RGS function have been implicated in a wide range of disease states, leading to many researchers focusing on controlling the action of these regulatory proteins. Previous studies have centered on reducing or inhibiting the action...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epinephrine
• Share to GTP-Binding Protein alpha Subunits, Gi-Go