Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).

doi:10.1002/ijc.28042

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).

International journal of cancer - 15 Jul 2013

Tsilidis Konstantinos K, Travis Ruth C, Appleby Paul N, Allen Naomi E, Lindström Sara, Albanes Demetrius, Ziegler Regina G, McCullough Marjorie L, Siddiq Afshan, Barricarte Aurelio, Berndt Sonja I, Bueno-de-Mesquita H Bas, Chanock Stephen J, Crawford E David, Diver W Ryan, Gapstur Susan M, Giovannucci Edward, Gu Fangyi, Haiman Christopher A, Hayes Richard B, Hunter David J, Johansson Mattias, Kaaks Rudolf, Kolonel Laurence N, Kraft Peter, Le Marchand Loic, Overvad Kim, Polidoro Silvia, Riboli Elio, Schumacher Fredrick R, Stevens Victoria L, Trichopoulos Dimitrios, Virtamo Jarmo, Willett Walter C, Key Timothy J

Abstract excerpt

It has been hypothesized that a high intake of dairy protein may increase prostate cancer risk by increasing the production of insulin-like growth factor 1 (IGF-1). Several single nucleotide polymorphisms (SNPs) have been weakly associated with circulating concentrations of IGF-1 and IGF binding protein 3 (IGFBP-3), but none of these SNPs was associated with risk of prostate cancer. We examined whether an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Diet

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Insulin-Like Growth Factor I

Share to Models, Biological

Share to Odds Ratio

Share to Prostatic Neoplasms

Share to Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 23341348
DOI: 10.1002/ijc.28042
PMCID: PMC3656134

Genes

SSTR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).PMID 23341348Read ↗

Interactions between genome-wide significant genetic variants and circulating concentrations of insulin-like growth factor 1, sex hormones, and binding proteins in relation to prostate cancer risk in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.Semantic proximity Read ↗

Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.Semantic proximity Read ↗

A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians.Semantic proximity Read ↗

Genetic and plasma variation of insulin-like growth factor binding proteins in relation to prostate cancer incidence and survival.Semantic proximity Read ↗

IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).Semantic proximity Read ↗

Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.Semantic proximity Read ↗

Genetic and dietary determinants of insulin-like growth factor (IGF)-1 and IGF binding protein (BP)-3 levels among Chinese women.Semantic proximity Read ↗

Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort.Semantic proximity Read ↗

Prostate cancer risk in relation to selected genetic polymorphisms in insulin-like growth factor-I, insulin-like growth factor binding protein-3, and insulin-like growth factor-I receptor.Semantic proximity Read ↗

Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies.Semantic proximity Read ↗

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3.Semantic proximity Read ↗

IGF-1 and IGFBP-3 gene variants influence on serum levels and prostate cancer risk in African-Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.