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Article

Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies.

European journal of human genetics : EJHG - 1 Dec 2009

Chen Wensen, Wang Sumin, Tian Tian, Bai Jianling, Hu Zhibin, Xu Yan, Dong Jing, Chen Feng, Wang Xinru, Shen Hongbing

Abstract excerpt

Insulin-like growth factor 1 (IGF1) and its main binding protein, IGF-binding protein 3 (IGFBP3), play an important role in cancer development. Circulating levels and functional polymorphisms of IGF1 and IGFBP3 may be biomarkers of cancer development. However, the results of published studies remain conflicting rather than conclusive. We searched MEDLINE and EMBASE databases for all published studies related to...

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Identifiers

PMID: 19491931
DOI: 10.1038/ejhg.2009.86
PMCID: PMC2987015

Genes

IGFBP3
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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