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Article

Genetic and plasma variation of insulin-like growth factor binding proteins in relation to prostate cancer incidence and survival.

The Prostate - 1 Sept 2009

Johansson Mattias, McKay James D, Rinaldi Sabina, Wiklund Fredrik, Adami Hans-Olov, Grönberg Henrik, Kaaks Rudolf, Stattin Pär

Abstract excerpt

BACKGROUND: Binding proteins regulate bioavailability of insulin-like growth factor-I (IGF-I) in the circulation and affect apoptosis of tumor cells in the prostate. We analyzed genetic variation within genes coding for IGF binding proteins in relation to prostate cancer incidence and survival. We also investigated if circulating IGFBP3 affects prostate cancer-specific survival. MATERIALS AND METHODS: Eleven...

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Source

Identifiers

PMID: 19455605
DOI: 10.1002/pros.20972

Genes

IGFBP3
CAPS
IGFALS
IGFBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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