Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort.

doi:10.1158/1055-9965.EPI-06-0361

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Article

Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2006

Cheng Iona, Penney Kathryn L, Stram Daniel O, Le Marchand Loic, Giorgi Elena, Haiman Christopher A, Kolonel Laurence N, Pike Malcolm, Hirschhorn Joel, Henderson Brian E, Freedman Matthew L

Abstract excerpt

Collective evidence suggests that the insulin-like growth factor (IGF) system plays a role in prostate and breast cancer risk. IGF-binding proteins (IGFBP) are the principal regulatory molecules that modulate IGF-I bioavailability in the circulation and tissues. To examine whether inherited differences in the IGFBP1 and IGFBP3 genes influence prostate and breast cancer susceptibility, we conducted two large...

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Identifiers

PMID: 17035411
DOI: 10.1158/1055-9965.EPI-06-0361

Genes

IGFBP1
IGFBP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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