Article
Mutation of a NCKX eliminates glial microdomain calcium oscillations and enhances seizure susceptibility.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 Jan 2013
Melom Jan E, Littleton J Troy
Abstract excerpt
Glia exhibit spontaneous and activity-dependent fluctuations in intracellular Ca(2+), yet it is unclear whether glial Ca(2+) oscillations are required during neuronal signaling. Somatic glial Ca(2+) waves are primarily mediated by the release of intracellular Ca(2+) stores, and their relative imp...
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