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Article

Orchestration of stepwise synaptic growth by K+ and Ca2+ channels in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Nov 2010

Lee Jihye, Wu Chun-Fang

Abstract excerpt

Synapse formation is tightly associated with neuronal excitability. We found striking synaptic overgrowth caused by Drosophila K(+)-channel mutations of the seizure and slowpoke genes, encoding Erg and Ca(2+)-activated large-conductance (BK) channels, respectively. These mutants display two distinct patterns of "satellite" budding from larval motor terminus synaptic boutons. Double-mutant analysis indicates that...

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Identifiers

PMID: 21106821
DOI: 10.1523/JNEUROSCI.3448-10.2010
PMCID: PMC3075884

Genes

PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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