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<i>Nckx30c</i> , a <i>Drosophila</i> K <sup>+</sup> -dependent Na <sup>+</sup> /Ca <sup>2+</sup> exchanger, regulates temperature-sensitive convulsions and age-related neurodegeneration

2025-10-09

Abstract excerpt

Calcium (Ca 2+ ) homeostasis is fundamental to neuronal physiology, including in the regulation of membrane excitability and synaptic transmission. Disruptions in the ion transporters regulating Ca 2+ influx and efflux are clearly linked to seizure disorders and age-related neurodegenerative disease. Yet, the specific contributions of variants in genes encoding these transporters to neurological disease remain t...

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Literature Corpus work
821a53fa-44a7-5f3d-b805-8d5a62221805
DOI
10.1101/2025.10.08.681163
Open publication

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<i>Nckx30c</i> , a <i>Drosophila</i> K <sup>+</sup> -dependent Na <sup>+</sup> /Ca <sup>2+</sup> exchanger, regulates temperature-sensitive convulsions and age-related neurodegenerationDOI 10.1101/2025.10.08.681163
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