Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis.

Current biology : CB - 24 May 2011

Stawicki Tamara M, Zhou Keming, Yochem John, Chen Lihsia, Jin Yishi

Abstract excerpt

Neuronal networks operate over a wide range of activity levels, with both neuronal and nonneuronal cells contributing to the balance of excitation and inhibition. Activity imbalance within neuronal networks underlies many neurological diseases, such as epilepsy. The Caenorhabditis elegans locomotor circuit operates via coordinated activity of cholinergic excitatory and GABAergic inhibitory transmission. We have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Larva
Share to Ions
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophysiology

Share to Magnesium

Share to Receptors, Nicotinic

Share to Seizures

Share to TRPM Cation Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 21549603
DOI: 10.1016/j.cub.2011.03.070
PMCID: PMC4034270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis.PMID 21549603Read ↗

Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans.Semantic proximity Read ↗

A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans.Semantic proximity Read ↗

Neuronal transcriptome analyses reveal novel neuropeptide modulators of excitation and inhibition imbalance in C. elegans.Semantic proximity Read ↗

Differential regulation of TRPM channels governs electrolyte homeostasis in the C. elegans intestine.Semantic proximity Read ↗

Neuronal transcriptome analyses reveal novel neuropeptide modulators of excitation and inhibition imbalance in <i>C. elegans</i>Semantic proximity Read ↗

The potassium chloride cotransporter KCC-2 coordinates development of inhibitory neurotransmission and synapse structure in Caenorhabditis elegans.Semantic proximity Read ↗

Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulationSemantic proximity Read ↗

ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans.Semantic proximity Read ↗

Two types of chloride transporters are required for GABA(A) receptor-mediated inhibition in C. elegans.Semantic proximity Read ↗

Behavioral impact of neurotransmitter-activated G-protein-coupled receptors: muscarinic and GABAB receptors regulate Caenorhabditis elegans locomotion.Semantic proximity Read ↗

Endoplasmic reticulum proteins MCTP-1 and ESYT-2 support presynaptic function during sustained activity in Caenorhabditis elegans.Semantic proximity Read ↗

Paradigms for pharmacological characterization of C. elegans synaptic transmission mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.