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Article

The effects of APOE-ε4 on the BOLD response.

Neurobiology of aging - 1 Feb 2012

Trachtenberg Aaron J, Filippini Nicola, Mackay Clare E

Abstract excerpt

In the last decade, functional magnetic resonance imaging (fMRI) has emerged as a tool to study changes in brain function associated with a genetic risk for Alzheimer's disease (AD), with a particular focus on the effects of the APOE-ε4 allele. This review compiles the existing literature concerning the effects of APOE genotype on the blood oxygen level dependent (BOLD) response, measured during task-based...

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Source

Identifiers

PMID: 20409610
DOI: 10.1016/j.neurobiolaging.2010.03.009

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The effects of APOE-ε4 on the BOLD response.PMID 20409610Read ↗

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Differential effects of the APOE genotype on brain function across the lifespan.Semantic proximity Read ↗

Interaction of age and APOE genotype on cerebral blood flow at rest.Semantic proximity Read ↗

Alzheimer's disease patients not carrying the apolipoprotein E ε4 allele show more severe slowing of oscillatory brain activity.Semantic proximity Read ↗

APOE related alterations in cerebral activation even at college age.Semantic proximity Read ↗

Differential effects of the ApoE4 genotype on brain structure and function.Semantic proximity Read ↗

Apolipoprotein E ε4 allele impairs cortical activity in healthy aging and Alzheimer's disease.Semantic proximity Read ↗

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s diseaseSemantic proximity Read ↗

The effects of APOE on the functional architecture of the resting brain.Semantic proximity Read ↗

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