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Neuroimaging and <i>APOE</i> Genotype: A Systematic Qualitative Review

1 Jan 2007

Abstract excerpt

Apolipoprotein E (APOE) is the major genetic risk factor for late-onset Alzheimer's disease (AD) and has also been implicated in cardiovascular disease, cognitive decline and cognitive changes in healthy ageing. The aim of this paper is to systematically review and critically assess the association between the APOE genotype and structural/functional cerebral changes as evidenced by brain imaging studies. A second...

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PMID: 17911980
DOI: 10.1159/000109150

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