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Article

Associations between age, sex, APOE genotype, and regional vascular physiology in typically aging adults.

NeuroImage - 15 Jul 2023

Damestani Nikou L, Jacoby John, Yadav Shrikanth M, Lovely Allison E, Michael Aurea, Terpstra Melissa, Eshghi Marziye, Rashid Barnaly, Cruchaga Carlos, Salat David H, Juttukonda Meher R

Abstract excerpt

Altered blood flow in the human brain is characteristic of typical aging. However, numerous factors contribute to inter-individual variation in patterns of blood flow throughout the lifespan. To better understand the mechanisms behind such variation, we studied how sex and APOE genotype, a primary genetic risk factor for Alzheimer's disease (AD), influence associations between age and brain perfusion measures. We...

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Identifiers

PMID: 37187365
DOI: 10.1016/j.neuroimage.2023.120167
PMCID: PMC10339339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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