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Article

A novel mouse Dscam mutation inhibits localization and shedding of DSCAM.

PloS one - 1 Jan 2012

Schramm R Dee, Li Shuai, Harris Belinda S, Rounds Ryan P, Burgess Robert W, Ytreberg F Marty, Fuerst Peter G

Abstract excerpt

The differential adhesion hypothesis of development states that patterning of organisms, organs and tissues is mediated in large part by expression of cell adhesion molecules. The cues provided by cell adhesion molecules are also hypothesized to facilitate specific connectivity within the nervous system. In this study we characterize a novel mouse mutation in the gene Dscam (Down Syndrome Cell Adhesion Molecule)....

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Source

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Identifiers

PMID: 23300735
DOI: 10.1371/journal.pone.0052652
PMCID: PMC3530462

Genes

DSCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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