Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel null allele of mouse DSCAM survives to adulthood on an inbred C3H background with reduced phenotypic variability.

Genesis (New York, N.Y. : 2000) - 1 Oct 2010

Fuerst Peter G, Harris Belinda S, Johnson Kenneth R, Burgess Robert W

Abstract excerpt

DSCAMs are cell adhesion molecules that play several important roles in neurodevelopment. Mouse alleles of Dscam identified to date do not survive on an inbred C57BL/6 background, complicating analysis of DSCAM-dependent developmental processes because of phenotypic variability related to the segregating backgrounds needed for postnatal survival. A novel spontaneous allele of Dscam, hereafter referred to as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pairing
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frameshift Mutation

Share to Homozygote

Share to Mice, Inbred C3H

Share to Mice, Knockout

Share to Neurites

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 20715164
DOI: 10.1002/dvg.20662
PMCID: PMC2987671

Genes

DSCAM

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel null allele of mouse DSCAM survives to adulthood on an inbred C3H background with reduced phenotypic variability.PMID 20715164Read ↗

Highlighted article: "A novel null allele of mouse Dscam survives to adulthood on an inbred C3H background with reduced phenotypic variability" by Fuerst, Harris, Johnson and Burgess.Semantic proximity Read ↗

A novel mouse Dscam mutation inhibits localization and shedding of DSCAM.Semantic proximity Read ↗

Cell autonomy of DSCAM function in retinal development.Semantic proximity Read ↗

A new mouse mutant with a discrete mutation in Pcdhgc5 reveals that the Protocadherin γC5 isoform is not essential for dendrite arborization in the cerebral cortex.Semantic proximity Read ↗

Dscam diversity is essential for neuronal wiring and self-recognition.Semantic proximity Read ↗

CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4.Semantic proximity Read ↗

CRISPR/Cas9 interrogation of the mouse <i>Pcdhg</i> gene cluster reveals a crucial isoform-specific role for <i>Pcdhgc4</i>Semantic proximity Read ↗

Novel axon projection after stress and degeneration in the Dscam mutant retina.Semantic proximity Read ↗

Assessing vision and autism spectrum disorder-relevant social interaction phenotypes in Dscam mice.Semantic proximity Read ↗

Functional analysis of the epilepsy gene <i>Pcdh19</i> using a novel conditional GFP-reporter mouse modelSemantic proximity Read ↗

Cellular and behavioral characterization of <i>Pcdh19</i> mutant mice: subtle molecular changes, increased exploratory behavior and an impact of social environmentSemantic proximity Read ↗

Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.