Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.

Molecular vision - 1 Jan 2014

de Andrade Gabriel Belem, Kunzelman Landon, Merrill Morgan M, Fuerst Peter G

Abstract excerpt

PURPOSE: The Down syndrome cell adhesion molecule (Dscam) gene is required for normal dendrite arborization and lamination in the mouse retina. In this study, we characterized the developmental localization of the DSCAM protein to better understand the postnatal stages of retinal development during which laminar disorganization occur in the absence of the protein. METHODS: Immunohistochemistry and colocalization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catenins
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendrites

Share to Neurites

Share to Neurogenesis

Share to Retinal Ganglion Cells

Share to Synapses

Share to Tight Junctions

Source

Open in PubMed Open full text

Identifiers

PMID: 25352748
PMCID: PMC4191645

Genes

DSCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.PMID 25352748Read ↗

A novel mouse Dscam mutation inhibits localization and shedding of DSCAM.Semantic proximity Read ↗

Cell autonomy of DSCAM function in retinal development.Semantic proximity Read ↗

DSCAM localization and function at the mouse cone synapse.Semantic proximity Read ↗

DSCAM promotes refinement in the mouse retina through cell death and restriction of exploring dendrites.Semantic proximity Read ↗

Novel axon projection after stress and degeneration in the Dscam mutant retina.Semantic proximity Read ↗

DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse modelsSemantic proximity Read ↗

DSCAM contributes to dendrite arborization and spine formation in the developing cerebral cortex.Semantic proximity Read ↗

Assessing vision and autism spectrum disorder-relevant social interaction phenotypes in Dscam mice.Semantic proximity Read ↗

Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas.Semantic proximity Read ↗

<i>Dscam</i> gene triplication causes neocortical overinhibition in Down syndromeSemantic proximity Read ↗

DSCAM promotes axon fasciculation and growth in the developing optic pathway.Semantic proximity Read ↗

Restoring DSCAM expression rescues neuronal morphology and axon guidance deficits in Down syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.