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Article

DSCAM contributes to dendrite arborization and spine formation in the developing cerebral cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Nov 2012

Maynard Kristen R, Stein Elke

Abstract excerpt

Down syndrome cell adhesion molecule, or DSCAM, has been implicated in many neurodevelopmental processes including axon guidance, dendrite arborization, and synapse formation. Here we show that DSCAM plays an important role in regulating the morphogenesis of cortical pyramidal neurons in the mouse. We report that DSCAM expression is developmentally regulated and localizes to synaptic plasma membranes during a...

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Source

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Identifiers

PMID: 23175819
DOI: 10.1523/JNEUROSCI.2811-12.2012
PMCID: PMC6621782

Genes

DSCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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