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Article

Novel axon projection after stress and degeneration in the Dscam mutant retina.

Molecular and cellular neurosciences - 1 Mar 2016

Fernandes K A, Bloomsburg S J, Miller C J, Billingslea S A, Merrill M M, Burgess R W, Libby R T, Fuerst P G

Abstract excerpt

The Down syndrome cell adhesion molecule gene (Dscam) is required for normal dendrite patterning and promotes developmental cell death in the mouse retina. Loss-of-function studies indicate that Dscam is required for refinement of retinal ganglion cell (RGC) axons in the lateral geniculate nucleus, and in this study we report and describe a requirement for Dscam in the maintenance of RGC axon projections within...

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Source

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Identifiers

PMID: 26691152
DOI: 10.1016/j.mcn.2015.12.003
PMCID: PMC4761494

Genes

JUN
DSCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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