Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell autonomy of DSCAM function in retinal development.

Developmental biology - 15 Jan 2012

Fuerst Peter G, Bruce Freyja, Rounds Ryan P, Erskine Lynda, Burgess Robert W

Abstract excerpt

Cell adhesion molecules (CAMs) provide identifying cues by which neural architecture is sculpted. The Down Syndrome Cell Adhesion Molecule (DSCAM) is required for many neurodevelopmental processes in different species and also has several potential mechanisms of activity, including homophilic adhesion, homophilic repulsion and heterophilic interactions. In the mouse retina, Dscam is expressed in many, but not all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Cell Adhesion Molecules
Share to Cell Count

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Death

Share to Dendrites

Share to Gene Targeting

Share to Mosaicism

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 22063212
DOI: 10.1016/j.ydbio.2011.10.028
PMCID: PMC3246579

Genes

DSCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell autonomy of DSCAM function in retinal development.PMID 22063212Read ↗

DSCAM promotes refinement in the mouse retina through cell death and restriction of exploring dendrites.Semantic proximity Read ↗

A novel mouse Dscam mutation inhibits localization and shedding of DSCAM.Semantic proximity Read ↗

DSCAM localization and function at the mouse cone synapse.Semantic proximity Read ↗

Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.Semantic proximity Read ↗

Dscam diversity is essential for neuronal wiring and self-recognition.Semantic proximity Read ↗

Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas.Semantic proximity Read ↗

Assessing vision and autism spectrum disorder-relevant social interaction phenotypes in Dscam mice.Semantic proximity Read ↗

Novel axon projection after stress and degeneration in the Dscam mutant retina.Semantic proximity Read ↗

DSCAM promotes axon fasciculation and growth in the developing optic pathway.Semantic proximity Read ↗

The Down Syndrome Critical Region Regulates Retinogeniculate RefinementSemantic proximity Read ↗

<i>Dscam</i> gene triplication causes neocortical overinhibition in Down syndromeSemantic proximity Read ↗

Restoring DSCAM expression rescues neuronal morphology and axon guidance deficits in Down syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.