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Article

Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases.

Genetics - 1 Mar 2013

Ansai Satoshi, Sakuma Tetsushi, Yamamoto Takashi, Ariga Hiroyoshi, Uemura Norihito, Takahashi Ryosuke, Kinoshita Masato

Abstract excerpt

Transcription activator-like effector nucleases (TALENs) have become powerful tools for targeted genome editing. Here we demonstrate efficient targeted mutagenesis in medaka (Oryzias latipes), which serves as an excellent vertebrate model for genetics and genomics. We designed and constructed a p...

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Source

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Identifiers

PMID: 23288935
DOI: 10.1534/genetics.112.147645
PMCID: PMC3583995

Genes

PARK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23288935-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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