Article
Intron-based genomic editing: a highly efficient method for generating knockin zebrafish.
Oncotarget - 20 Jul 2015
Li Jia, Zhang Baibing, Bu Jiwen, Du Jiulin
Abstract excerpt
The TALEN and CRISPR/Cas9 nuclease systems have been extensively utilized in genomic engineering of model organisms. In zebrafish, the nuclease systems have been successfully applied in generating loss-of-function knockout lines. However, genome-specific knockin techniques in zebrafish are still at the beginning. In this perspective, we briefly summarize the recent progresses on knockin approaches in zebrafish...
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