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Article

Association of the innate immunity and inflammation pathway with advanced prostate cancer risk.

PloS one - 1 Jan 2012

Kazma Rémi, Mefford Joel A, Cheng Iona, Plummer Sarah J, Levin Albert M, Rybicki Benjamin A, Casey Graham, Witte John S

Abstract excerpt

Prostate cancer is the most frequent and second most lethal cancer in men in the United States. Innate immunity and inflammation may increase the risk of prostate cancer. To determine the role of innate immunity and inflammation in advanced prostate cancer, we investigated the association of 320 single nucleotide polymorphisms, located in 46 genes involved in this pathway, with disease risk using 494 cases with...

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Source

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Identifiers

PMID: 23272139
DOI: 10.1371/journal.pone.0051680
PMCID: PMC3522730

Genes

OAS1
OAS2
TLR1
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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