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Article

Toll-like receptor-associated sequence variants and prostate cancer risk among men of African descent.

Genes and immunity - 1 Sept 2013

Rogers E N, Jones D Z, Kidd N C, Yeyeodu S, Brock G, Ragin C, Jackson M, McFarlane-Anderson N, Tulloch-Reid M, Sean Kimbro K, Kidd L R

Abstract excerpt

Recent advances demonstrate a relationship between chronic/recurrent inflammation and prostate cancer (PCA). Among inflammatory regulators, toll-like receptors (TLRs) have a critical role in innate immune responses. However, it remains unclear whether variant TLR genes influence PCA risk among men of African descent. Therefore, we evaluated the impact of 32 TLR-associated single-nucleotide polymorphisms (SNPs) on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23657238
DOI: 10.1038/gene.2013.22
PMCID: PMC3743959

Genes

IRAK4
TLR2
TLR6
TOLLIP

Provenance

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