Article
Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2007
Chen Yen-Ching, Giovannucci Edward, Kraft Peter, Lazarus Ross, Hunter David J
Abstract excerpt
BACKGROUND: Chronic inflammation may be a risk factor for prostate cancer. Previously, we found significant associations between single nucleotide polymorphisms (SNPs) and haplotypes in Toll-like receptor (TLR) 4 and the risk of prostate cancer. TLR6, TLR1, and TLR10 are also involved in the pathogen-mediated inflammation pathway. A Swedish study observed associations between sequence variants in the...
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