Article
Sequence variants of Toll-like receptor 4 (TLR4) and the risk of prostate cancer in Korean men.
World journal of urology - 1 Apr 2012
Kim Hae Jong, Bae Joon Seol, Chang In Ho, Kim Kyung Do, Lee Jaehyouk, Shin Hyoung Doo, Lee Ji Youl, Kim Wun-Jae, Kim Wonyong, Myung Soon Chul
Abstract excerpt
PURPOSE: Chronic inflammation has been considered a potential risk factor for prostate cancer. Toll-like receptors (TLRs) are important in the innate immune response to pathogens and in cross talk between innate immunity and adaptive immunity. In this study, sequence variants in the TLR4 gene were investigated to determine whether they were associated with prostate cancer risk in a Korean cohort. METHODS: An...
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