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Article

Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.

Journal of the National Cancer Institute - 6 Apr 2005

Sun Jielin, Wiklund Fredrik, Zheng S Lilly, Chang Baoli, Bälter Katarina, Li Liwu, Johansson Jan-Erik, Li Ge, Adami Hans-Olov, Liu Wennuan, Tolin Amy, Turner Aubrey R, Meyers Deborah A, Isaacs William B, Xu Jianfeng, Grönberg Henrik

Abstract excerpt

BACKGROUND: Chronic inflammation plays an important role in several human cancers and may be involved in the etiology of prostate cancer. Toll-like receptors (TLRs) are important in the innate immune response to pathogens and in cross-talk between innate immunity and adaptive immunity. Our previous finding of an association of TLR4 gene sequence variants and prostate cancer risk provides evidence for a role of...

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Identifiers

PMID: 15812078
DOI: 10.1093/jnci/dji070

Genes

TLR1
TLR10
TLR6
CAPS
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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