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Article

MTHFD1 polymorphism as maternal risk for neural tube defects: a meta-analysis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Apr 2015

Zheng Jinyu, Lu Xiaocheng, Liu Hao, Zhao Penglai, Li Kai, Li Lixin

Abstract excerpt

Recently, the association between methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) G1958A polymorphism and neural tube defects (NTD) susceptibility has been widely investigated; however, the results remained inconclusive. Hence, we conducted a meta-analysis to evaluate the effect of MTHFD1 G1958A polymorphism on NTD. The relative literatures were identified by search of the electronic databases PubMed, MEDLINE,...

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Source

Identifiers

PMID: 25502174
DOI: 10.1007/s10072-014-2035-7

Genes

MTHFD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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