Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of quaternary structure and enhancement of ligand binding by the K-turn of tandem glycine riboswitches.

RNA (New York, N.Y.) - 1 Feb 2013

Baird Nathan J, Ferré-D'Amaré Adrian R

Abstract excerpt

Most known glycine riboswitches have two homologous aptamer domains arranged in tandem and separated by a short linker. The two aptamers associate through reciprocal "quaternary" interactions that have been proposed to result in cooperative glycine binding. Recently, the interaptamer linker was found to form helix P0 with a previously unrecognized segment 5' to the first aptamer domain. P0 was shown to increase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aptamers, Nucleotide
Share to Bacillus subtilis
Share to Calorimetry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Magnesium

Share to Nucleotide Motifs

Share to Riboswitch

Share to Scattering, Small Angle

Share to Vibrio cholerae

Source

Open in PubMed Open full text

Identifiers

PMID: 23249744
DOI: 10.1261/rna.036269.112
PMCID: PMC3543082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of quaternary structure and enhancement of ligand binding by the K-turn of tandem glycine riboswitches.PMID 23249744Read ↗

An energetically beneficial leader-linker interaction abolishes ligand-binding cooperativity in glycine riboswitches.Semantic proximity Read ↗

Ligand binding by the tandem glycine riboswitch depends on aptamer dimerization but not double ligand occupancy.Semantic proximity Read ↗

In Vivo Behavior of the Tandem Glycine Riboswitch in Bacillus subtilis.Semantic proximity Read ↗

A glycine-dependent riboswitch that uses cooperative binding to control gene expression.Semantic proximity Read ↗

The asymmetry and cooperativity of tandem glycine riboswitch aptamers.Semantic proximity Read ↗

Aromatic rescue of glycine in beta sheets.Semantic proximity Read ↗

Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch.Semantic proximity Read ↗

Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain.Semantic proximity Read ↗

In-silico studies on thermodynamics of ligand binding to Fluoride riboswitch aptamerSemantic proximity Read ↗

Contrasting roles for symmetrically disposed beta-turns in the folding of a small protein.Semantic proximity Read ↗

Ligand-mediated and tertiary interactions cooperatively stabilize the P1 region in the guanine-sensing riboswitch.Semantic proximity Read ↗

Aggregation gatekeeper and controlled assembly of Trpzip β-hairpins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.