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Article

An energetically beneficial leader-linker interaction abolishes ligand-binding cooperativity in glycine riboswitches.

RNA (New York, N.Y.) - 1 Mar 2012

Sherman Eileen M, Esquiaqui Jackie, Elsayed Galal, Ye Jing-Dong

Abstract excerpt

Comprised of two aptamers connected by a short nucleotide linker, the glycine riboswitch was the first example of naturally occurring RNA elements reported to bind small organic molecules cooperatively. Earlier works have shown binding of glycine to the second aptamer allows tertiary interactions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22279151
DOI: 10.1261/rna.031286.111
PMCID: PMC3285937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22279151-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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