Article

In-silico studies on thermodynamics of ligand binding to Fluoride riboswitch aptamer

2024-06-26

Abstract excerpt

Riboswitch is a non-coding messenger RNA (m-RNA) whose aptamer domain binds cognate ligands and subsequently undergoes conformational changes in the expression platform leading to the regulation of gene expression. Fluoride riboswitch has immense pharmacological potential due to its presence in some human bacterial pathogens. Several experimental studies shed light on the bacterial defense mechanism of Fluoride ri...

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Literature Corpus work: e34fdc8c-fa94-59e2-b9f2-d60487262fb1
DOI: 10.1101/2024.06.23.600262

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In-silico studies on thermodynamics of ligand binding to Fluoride riboswitch aptamerDOI 10.1101/2024.06.23.600262Read

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