Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional repeats (TGYCC)n in the p53-inducible gene 3 (PIG3) promoter and susceptibility to squamous cell carcinoma of the head and neck.

Carcinogenesis - 1 Apr 2013

Guan Xiaoxiang, Liu Zhensheng, Wang Luo, Wang Li-E, Sturgis Erich M, Wei Qingyi

Abstract excerpt

A polymorphic pentanucleotide microsatellite sequence (TGYCC)n within the p53-inducible gene 3 (PIG3) promoter is correlated with the extent of transcriptional activation by p53 and thought to modulate susceptibility to cancer. Using a PCR-silver staining-based single-strand conformation assay, we visualized variant genotypes of the PIG3 promoter (TGYCC)n motif in a subset of 100 subjects for each of four ethnic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Hispanic or Latino

Share to Intracellular Signaling Peptides and Proteins

Share to Proto-Oncogene Proteins

Share to Squamous Cell Carcinoma of Head and Neck

Share to Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 23241165
DOI: 10.1093/carcin/bgs388
PMCID: PMC3616663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional repeats (TGYCC)n in the p53-inducible gene 3 (PIG3) promoter and susceptibility to squamous cell carcinoma of the head and neck.PMID 23241165Read ↗

Association of the PIG3 promoter polymorphism with invasive bladder cancer in a Japanese population.Semantic proximity Read ↗

The AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations.Semantic proximity Read ↗

SNP rs1049430 in the 3'-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Genetic association study of intron variants in the forkhead box protein P3 gene in Chinese patients diagnosed with cervical cancer.Semantic proximity Read ↗

Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Functional single nucleotide polymorphisms of the RASSF3 gene and susceptibility to squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking.Semantic proximity Read ↗

Association study of the G-protein beta3 subunit C825T polymorphism with disease progression an overall survival in patients with head and neck squamous cell carcinoma.Semantic proximity Read ↗

CASP3 Polymorphisms and Risk of Squamous Cell Carcinoma of the Head and NeckSemantic proximity Read ↗

The GNAS1 T393C polymorphism predicts survival in patients with advanced squamous cell carcinoma of the larynx.Semantic proximity Read ↗

The functional SNP in the matrix metalloproteinase-3 promoter modifies susceptibility and lymphatic metastasis in esophageal squamous cell carcinoma but not in gastric cardiac adenocarcinoma.Semantic proximity Read ↗

Overall and relapse-free survival in oropharyngeal and hypopharyngeal squamous cell carcinoma are associated with genotypes of T393C polymorphism of the GNAS1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.