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Article

Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck.

Carcinogenesis - 1 Oct 2004

Li Guojun, Sturgis Erich M, Wang Li-E, Chamberlain Robert M, Amos Christopher I, Spitz Margaret R, El-Naggar Adel K, Hong Waun K, Wei Qingyi

Abstract excerpt

p73, a novel p53 homolog, has some p53-like activity and plays an important role in modulating cell-cycle control, apoptosis and cell growth. p73 regulates differentiation of head and neck squamous epithelium, and changes in p73 may lead to the development of squamous cell carcinoma of the head and neck (SCCHN). Two linked non-coding exon 2 polymorphisms (designated as G4C14-to-A4T14) were identified recently but...

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Identifiers

PMID: 15180941
DOI: 10.1093/carcin/bgh197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck.PMID 15180941Read ↗

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