Article
SNP rs1049430 in the 3'-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications in head and neck squamous cell carcinoma.
Biochimica et biophysica acta - 1 May 2015
Maiti Guru Prasad, Ghosh Amlan, Mondal Pinaki, Baral Aradhita, Datta Sayantan, Samadder Sudip, Nayak Sandeep P, Chakrabarti Jayanta, Biswas Jaydeep, Sikdar Nilabja, Chowdhury Shantanu, Roy Bidyut, Roychowdhury Susanta, Panda Chinmay Kumar
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the 3'-UTR region are emerging cis-regulatory factors associated with the occurrences of several human diseases. SH3GL2, which is located at chromosome 9p21-22, is associated with hyperplastic/mildly dysplastic lesions of the head and neck and has a long 3'-UTR with multiple SNPs. The aim of the present study was to determine the susceptible allele(s) in the 3'-UTR SNPs...
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