Article
Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking.
Cancer science - 1 Apr 2008
Wang Haijian, Liu Yang, Tan Wen, Zhang Yang, Zhao Naiqing, Jiang Yan, Lin Chengzhao, Hao Bingtao, Zhao Dan, Qian Ji, Lu Daru, Jin Li, Wei Qingyi, Lin Dongxin, He Fuchu
Abstract excerpt
The etiology of esophageal squamous cell carcinoma (ESCC) has been shown to be multifactorial, including genetic, epigenetic, and environmental factors, such as tobacco smoking. A variable number of tandem repeats (VNTR) polymorphism in the promoter region of SMYD3, a recently characterized histone lysine methyltransferase gene that is implicated in cell proliferation and carcinogenesis, has been shown to be...
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