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Article

Overall and relapse-free survival in oropharyngeal and hypopharyngeal squamous cell carcinoma are associated with genotypes of T393C polymorphism of the GNAS1 gene.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2008

Lehnerdt Goetz F, Franz Peter, Zaqoul Anwar, Schmitz Klaus J, Grehl Sara, Lang Stephan, Schmid Kurt W, Siffert Winfried, Jahnke Klaus, Frey Ulrich H

Abstract excerpt

PURPOSE: In previous studies, we have shown that the T allele of a specific single-nucleotide polymorphism (SNP) in the Galphas gene (T393C) correlates with increased Galphas expression and hence apoptosis. The T allele was associated with a favorable outcome in a variety of human cancers, e.g.,...

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PMID: 18347176
DOI: 10.1158/1078-0432.CCR-07-1605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18347176-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Overall and relapse-free survival in oropharyngeal and hypopharyngeal squamous cell carcinoma are associated with genotypes of T393C polymorphism of the GNAS1 gene.PMID 18347176Read ↗

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