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Article

Functional single nucleotide polymorphisms of the RASSF3 gene and susceptibility to squamous cell carcinoma of the head and neck.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2014

Guo Hongguang, Liu Hongliang, Wei Jianhua, Li Yangkai, Yu Hongping, Guan Xiaoxiang, Li-E Wang, Li Guojun, Sturgis Erich M, Wei Qingyi, Liu Zhensheng

Abstract excerpt

BACKGROUND: RASSF3 suppresses tumour formation through uncertain mechanisms, but it is an important gene of p53-dependent apoptosis. RASSF3 depletion impairs DNA repair after DNA damage, leading to polyploidy. The authors hypothesised that potential functional single-nucleotide polymorphisms (SNPs) of RASSF3 are associated with risk of squamous cell carcinoma of the head and neck (SCCHN). METHODS: The authors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, Tumor Suppressor

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Source

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Identifiers

PMID: 24295637
DOI: 10.1016/j.ejca.2013.11.009
PMCID: PMC3946894

Genes

RASSF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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