Article
The TRIMCyp genotype in four species of macaques in China.
Immunogenetics - 1 Mar 2013
Yu Chang-Qing, Na Lei, Lv Xiao-Ling, Liu Jian-Dong, Liu Xiao-Ming, Ji Fang, Zheng Yong-Hui, Du Hong-Li, Kong Xian-Gang, Zhou Jian-Hua
Abstract excerpt
The tripartite motif protein (TRIM)5α/CypA fusion protein TRIMCyp in Old World monkeys is generally considered unable to restrict HIV-1 replication. Monkeys with TRIMCyp can serve as a unique animal model for studies of HIV-1 infection. The present study investigated the distribution and expression status of TRIMCyp in four species of macaques originating from China and its borderlands: pigtail macaques (Macaca...
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