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Article

Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection.

Retrovirology - 9 Jun 2009

Kuang Yi-Qun, Tang Xia, Liu Feng-Liang, Jiang Xue-Long, Zhang Ya-Ping, Gao Guangxia, Zheng Yong-Tang

Abstract excerpt

BACKGROUND: The pig-tailed macaques are the only Old World monkeys known to be susceptible to human immunodeficiency virus type 1 (HIV-1) infection. We have previously reported that the TRIM5-Cyclophilin A (TRIMCyp) fusion in pig-tailed macaques (Macaca nemestrina) is dysfunctional in restricting HIV-1, which may explain why pig-tailed macaques are susceptible to HIV-1 infection. Similar results have also been...

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Identifiers

PMID: 19505341
DOI: 10.1186/1742-4690-6-58
PMCID: PMC2703620

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection.PMID 19505341Read ↗

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