Article
[TRIMCyp frequency of the cynomolgus macaque (Macaca fascicularis) in captivity in China].
Dong wu xue yan jiu = Zoological research - 1 Apr 2013
Tian Shuai, Meng Yu-Huan, Liu Ming-Yu, Sun Fei, Chen Jun-Hui, Du Hong-Li, Wang Xiao-Ning
Abstract excerpt
In most Old world monkey species, TRIM5α plays a role in combating retroviruses and restricting HIV-1. Alongside TRIM5α, the TRIMCyp fusion gene formed by the retrotransposition of a CypA pseudogene cDNA to 3' terminal or 3'-UTR of TRIM5 gene in these monkeys has become a key research area in anti HIV-1 factors. The regional differences, gene frequencies, genotypes, and retrovirus restrictive activities of...
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