Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Variable prevalence and functional diversity of the antiretroviral restriction factor TRIMCyp in Macaca fascicularis.

Journal of virology - 1 Oct 2011

Dietrich Elizabeth A, Brennan Greg, Ferguson Betsy, Wiseman Roger W, O'Connor David, Hu Shiu-Lok

Abstract excerpt

The retroviral restriction factor TRIMCyp, derived from the TRIM5 gene, blocks replication at a postentry step. TRIMCyp has so far been found in four species of Asian macaques, Macaca fascicularis, M. mulatta, M. nemestrina, and M. leonina. M. fascicularis is commonly used as a model for AIDS research, but TRIMCyp has not been analyzed in detail in this species. We analyzed the prevalence of TRIMCyp in samples...

Topics

Alleles
Animals
Antiviral Agents
China
Indonesia
Lentiviruses, Primate
Macaca fascicularis
Mauritius
Molecular Sequence Data
Philippines
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prevalence

Proteins

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 21795330
DOI: 10.1128/JVI.00097-11
PMCID: PMC3196437

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variable prevalence and functional diversity of the antiretroviral restriction factor TRIMCyp in Macaca fascicularis.PMID 21795330Read ↗

Geographical, genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis).Semantic proximity Read ↗

[TRIMCyp frequency of the cynomolgus macaque (Macaca fascicularis) in captivity in China].Semantic proximity Read ↗

Diversity of TRIM5α and TRIMCyp sequences in cynomolgus macaques from different geographical origins.Semantic proximity Read ↗

The TRIMCyp genotype in four species of macaques in China.Semantic proximity Read ↗

Evolution of the antiretroviral restriction factor TRIMCyp in Old World primates.Semantic proximity Read ↗

Independent evolution of an antiviral TRIMCyp in rhesus macaquesSemantic proximity Read ↗

TRIMCyp expression in Old World primates <i>Macaca nemestrina</i> and <i>Macaca fascicularis</i>Semantic proximity Read ↗

Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.Semantic proximity Read ↗

Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection.Semantic proximity Read ↗

Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.Semantic proximity Read ↗

Evolution of a TRIM5-CypA splice isoform in old world monkeys.Semantic proximity Read ↗

TRIM5 allelic polymorphism in macaque species/populations of different geographic origins: its impact on SIV vaccine studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.