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Article

FGFR4 profile as a prognostic marker in squamous cell carcinoma of the mouth and oropharynx.

PloS one - 1 Jan 2012

Dutra Roberta Lelis, de Carvalho Marcos Brasilino, Dos Santos Marcelo, Mercante Ana Maria da Cunha, Gazito Diana, de Cicco Rafael, Group Gencapo, Tajara Eloiza Helena, Louro Iúri Drumond, da Silva Adriana Madeira Álvares

Abstract excerpt

BACKGROUND: Fibroblast growth factor receptor 4 (FGFR4) is a member of a receptor tyrosine kinase family of enzymes involved in cell cycle control and proliferation. A common single nucleotide polymorphism (SNP) Gly388Arg variant has been associated with increased tumor cell motility and progression of breast cancer, head and neck cancer and soft tissue sarcomas. The present study evaluated the prognostic...

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Topics

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Share to Biomarkers, Tumor
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Mouth Neoplasms

Share to Oropharyngeal Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Share to Receptor, Fibroblast Growth Factor, Type 4

Source

Open in PubMed Open full text

Identifiers

PMID: 23226373
DOI: 10.1371/journal.pone.0050747
PMCID: PMC3511351

Genes

FGFR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FGFR4 profile as a prognostic marker in squamous cell carcinoma of the mouth and oropharynx.PMID 23226373Read ↗

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