Article
Prognostic Role of the FGFR4-388Arg Variant in Lung Squamous-Cell Carcinoma Patients With Lymph Node Involvement.
Clinical lung cancer - 1 Nov 2017
Quintanal-Villalonga Álvaro, Carranza-Carranza Andrés, Meléndez Ricardo, Ferrer Irene, Molina-Pinelo Sonia, Paz-Ares Luis
Abstract excerpt
BACKGROUND: The identification of prognostic biomarkers for lung squamous-cell carcinoma (SCC) pathology is crucial because of its poor prognosis. A variant of the FGFR4 (fibroblast growth factor receptor 4) gene, FGFR4-388Arg, has been associated with prognosis and is linked to oncogenesis in vitro in several types of cancer. We analyzed the association of this variant with prognosis and downstream signaling...
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