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Article

The fibroblast growth factor receptor 4 (FGFR4) Arg388 allele correlates with survival in head and neck squamous cell carcinoma.

Experimental and molecular pathology - 1 Feb 2007

da Costa Andrade Valéria Cristina, Parise Orlando, Hors Cora Pereira, de Melo Martins Poliana Cristina, Silva Alexandre Pacheco, Garicochea Bernardo

Abstract excerpt

BACKGROUND: The increased expression of the fibroblast growth factor receptor 4 (FGFR4) has been identified in many human cancers. Recently, a single nucleotide polymorphism changing the sense codon 388 from glycine to arginine was identified in the FGFR4 gene. The FGFR4 Arg(388) allele was found to be associated with a poor prognosis for positive node breast cancer, high-grade soft-tissue sarcoma, colon...

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Topics

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Share to Alleles
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Prognosis

Share to Receptor, Fibroblast Growth Factor, Type 4

Share to Survival Analysis

Source

Identifiers

PMID: 17084840
DOI: 10.1016/j.yexmp.2006.05.003

Genes

FGFR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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