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Article

Fibroblast growth factor receptor 4 gene (FGFR4) 388Arg allele predicts prolonged survival and platinum sensitivity in advanced ovarian cancer.

International journal of cancer - 15 Aug 2012

Marmé Frederik, Hielscher Thomas, Hug Sarah, Bondong Sandra, Zeillinger Robert, Castillo-Tong Dan Cacsire, Sehouli Jalid, Braicu Ioana, Vergote Ignace, Isabella Cadron, Mahner Sven, Ferschke Irmgard, Rom Joachim, Sohn Christof, Schneeweiss Andreas, Altevogt Peter

Abstract excerpt

FGFR4 has been shown to play an important role in the etiology and progression of solid tumors. A single nucleotide polymorphism (SNP) within the FGFR4 gene has previously been linked to prognosis and response to chemotherapy in breast cancer and other malignancies. This study evaluates the relevance of this SNP in advanced ovarian cancer. FGFR4-genotype was analyzed in 236 patients recruited as part of the OVCAD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22034009
DOI: 10.1002/ijc.27329

Genes

FGFR4

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