Article
FGFR4 Gly388Arg polymorphism and prognosis of breast and colorectal cancer.
Oncology reports - 1 Aug 2005
Spinola Monica, Leoni Vera Piera, Tanuma Jun-Ichi, Pettinicchio Angela, Frattini Milo, Signoroni Stefano, Agresti Roberto, Giovanazzi Riccardo, Pilotti Silvana, Bertario Lucio, Ravagnani Fernando, Dragani Tommaso A
Abstract excerpt
A functional Gly388Arg variation in the FGFR4 gene has been reported to be associated with breast and colorectal cancer prognostic parameters. To further examine the functional role of this genetic polymorphism at the population level, we assessed the presence of the Arg388 allele in 142 breast carcinoma patients, 179 colorectal carcinoma patients and 220 general population controls with respect to an association...
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