Article
FGFR4 Is a Potential Predictive Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2015
Koole Koos, van Kempen Pauline M W, van Bockel Liselotte W, Smets Timo, van der Klooster Zoë, Dutman Annemiek C, Peeters Ton, Koole Ron, van Diest Paul, van Es Robert J J, Willems Stefan M
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate whether fibroblast growth factor receptor 4 (FGFR4) could serve as a potential therapeutic target, prognostic biomarker or biomarker predicting radiotherapy sensitivity in oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma (OPSCC). METHODS: FGFR4 immunohistochemistry and FGFR4/CEN5q FISH were performed on tissue microarrays from 212...
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