Article
Involvement of the FGFR4 Arg388 allele in head and neck squamous cell carcinoma.
International journal of cancer - 20 Aug 2004
Streit Sylvia, Bange Johannes, Fichtner Alexander, Ihrler Stephan, Issing Wolfgang, Ullrich Axel
Abstract excerpt
Fibroblast growth factor receptors (FGFRs) have been implicated in various forms of human hyperproliferative disorders such as cancers of the cervix and bladder. We investigated the expression pattern of FGFR4 and the clinical significance of the recently identified Gly/Arg polymorphism (388) in head and neck squamous cell carcinomas (HNSCCs) of the oral cavity and the oropharynx. Sections from 104...
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