Article
FGFR4 polymorphism, TP53 mutation, and their combinations are prognostic factors for oral squamous cell carcinoma.
Oncology reports - 1 Mar 2010
Tanuma Jun-Ichi, Izumo Toshiyuki, Hirano Masato, Oyazato Yoshitaka, Hori Fumiya, Umemura Eri, Shisa Hayase, Hiai Hiroshi, Kitano Motoo
Abstract excerpt
The genotype of the fibroblast growth factor receptor 4 (FGFR4) gene and TP53 mutation have been reported as prognostic factors for cancers of the head and neck, bladder, breast and colon. To determine whether they are applicable for oral squamous cell carcinoma (OSCC), we investigated these two genes in OSCC samples from 150 patients who had undergone radical surgery and in 100 cancer-free individuals. In OSCC,...
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