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Article

Is FGFR4 Gly388Arg missense variant a suitable prognostic marker in neuroblastoma?

Journal of cancer research and therapeutics - 1 Jan 2000

Katarzyna Szewczyk

Abstract excerpt

Context: Evidence suggested that FGFR4-Arg388 allele is frequently detected in multiple cancers with rapid progression and unfavorable clinical implications. Aims: It was investigated whether the FGFR4 missense variant (Gly388Arg) could serve as a prognostic biomarker and therapeutic target in neuroblastoma (NB). Materials and Methods: FGFR4 genotypes were determined by DNA sequencing in 34 NB tumors. The results...

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Share to Receptor, Fibroblast Growth Factor, Type 4

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PMID: 37006072
DOI: 10.4103/jcrt.jcrt_1516_21

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