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Functional FGFR4 Gly388Arg Polymorphism Predicts Prognosis in Lung Adenocarcinoma Patients

2 Aug 2005

Abstract excerpt

PURPOSE: Fibroblast growth factor receptor 4 (FGFR4) is a member of a family of transmembrane receptors with ligand-induced tyrosine kinase activity. The Gly388Arg polymorphism in the FGFR4 gene was reported to modulate cancer cell migration in vitro and to be associated with breast, colon, and prostate cancer prognostic parameters. The purpose of this study was to investigate the involvement of the FGFR4...

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Identifiers

PMID: 16061909
DOI: 10.1200/jco.2005.17.350

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Functional FGFR4 Gly388Arg Polymorphism Predicts Prognosis in Lung Adenocarcinoma PatientsPMID 16061909Read ↗

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